Now Panorama® offers screening for twin and egg donor pregnancies! Panorama® is the first Non Invasive DNA screen for fetal chromosomal abnormalities providing: Zigosity information; Individual fetal fractions for dizygotic twins; Fetal sex for each twin; Likelihood of monosomy X for monozygotic twins. Panorama® screened for trisomies 13, 18 and 21 in twin pregnancies with a combined s ensitivity […]
Molecular investigations, Prenatal diagnosis, Genetic, Natera, Next Generation Sequencing, NIPT, Non Invasive Prenatal Testing, Panorama, Test DNA fetale, Test prenatale su sangue materno
Microgenomics Laboratory offers services of prenatal diagnosis using the array-CGH technique. Array-CGH analysis in prenatal period can detect possible genomic alterations in a fetus. The test uses DNA obtained from amniotic fluid or CVS to investigate the whole genome in a single test. Below we provide a detailed brochure about the use of molecular karyotype in prenatal period.
Molecular investigations, CGH-Array, Brochure, Molecular karyotype, Prenatal diagnosis
Array-CGH analysis in prenatal diagnosis can detect possible genomic alterations in a fetus. The test uses DNA obtained from amniotic fluid or CVS to investigate the whole genome in a single test. Prenatal array-CGH guarantees a much higher sensitivity allowing to detect CNVs that would go undetected with the conventional karyotyping. Array-CGH does not need cell cultures. This allows a reduction of the analysis […]
Molecular investigations, CGH-Array, Brochure, Molecular karyotype, Prenatal diagnosis, List of pathologies
A position statement from the cytogenetics working group of the Italian Society of Human Genetics (SIGU). Ultrasound Obstet Gynecol. 2012 Apr;39(4):384-8. doi: 10.1002/uog.11092. Autori: Novelli A, Grati FR, Ballarati L, Bernardini L, Bizzoco D, Camurri L, Casalone R, Cardarelli L, Cavalli P, Ciccone R, Clementi M, Dalprà L, Gentile M, Gelli G,Grammatico P, Malacarne M, Nardone AM, Pecile V, Simoni G, Zuffardi O, Giardino D. Abstract: A precise guideline establishing chromosomal microarray analysis (CMA) applications […]
Molecular investigations, CGH-Array, Molecular karyotype, Prenatal diagnosis